Vittorio Colizzi, coordinator of STARBIOS2 project, is Full professor of General Pathology and Immunology, and Director of UNESCO Chair in Biotechnology and Bioethics at University of Rome “Tor Vergata”. He will talk about the aim of the project and the concept of Responsible Research and Innovation (RRI). 1. How would you describe the concept of Responsible Research and Innovation? In short, RRI is an inclusive approach to research and innovation (R&I). It aims to better align both the process and outcomes of R&I with the values, needs and expectations of European society, and to ensure that societal actors work together during the whole research and innovation process. 2. Why is RRI important for the advancement of the research? Research and innovation have never been carried out in isolation from the social, political and economic context. But the RRI helps us to highlight an important fact: one of the main risk, for European research is its inadequate connection with society. The loose connection between research and society could make European research unable to address the key development problems, unable to exploit its potential for innovation and competitiveness in the global market, and socially isolated or contested (see the case of the attitude of many citizens towards the vaccinations). For these reasons, RRI is important, because it focuses on the subject of a stronger R&I, and even more relevant with respect to society; a society of which R&I itself is an integral part. 3. Could you describe the 5 key issues …